Search on: CATHEPSIN B LIKE PROTEINASE 
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Descriptor English:   Cathepsin B 
Descriptor Spanish:   Catepsina B 
Descriptor Portuguese:   Catepsina B 
Synonyms English:   Cathepsin B-Like Proteinase
Cathepsin B1
Cathepsin B Like Proteinase
Proteinase, Cathepsin B-Like  
Tree Number:   D08.811.277.656.224.125
D08.811.277.656.262.500.133
D08.811.277.656.300.200.133
Definition English:   A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS. 
History Note English:   87 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23222 
Unique Identifier:   D002401 

Occurrence in VHL: 		 

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